Mucosa-associated lymphoid tissue lymphoma in conjunctiva

Area of Science:

• Ophthalmology
• Oncology
• Hematology

Background:

• Conjunctival lymphomas are rare neoplasms.
• Primary mucosa-associated lymphoid tissue (MALT) lymphoma of the conjunctiva is an uncommon entity.
• Accurate diagnosis is essential for appropriate management and prognosis.

Observation:

• A case of primary conjunctival MALT lymphoma presented as a slowly growing, salmon-colored mass at the limbus of the left eye.
• Histopathological examination revealed a diffuse, low-grade lymphoma.
• Immunohistochemical analysis confirmed B-cell lineage, with tumor cells positive for CD45 and CD20, and negative for CD3, CD5, CD10, and CD43.

Findings:

• The histological and immunohistochemical findings were consistent with a diagnosis of primary conjunctival MALT lymphoma.
• The tumor exhibited characteristic features of a marginal zone B-cell lymphoma.

Implications:

• This case highlights the importance of recognizing rare conjunctival malignancies.
• Early diagnosis and appropriate management of conjunctival MALT lymphoma are associated with an excellent prognosis.
• Further research into the specific characteristics and optimal treatment strategies for conjunctival MALT lymphoma is warranted.