Related Experiment Video
Updated: Jul 2, 2026
A Periprosthetic Joint Candida albicans Infection Model in Mouse
Published on: February 2, 2024
The use of qualitative cultures for detecting infection in open tibial fractures
A D'Souza1, N Rajagopalan, R S Amaravati
1Department of Orthopaedics, St John's Medical College Hospital, Bangalore, India.
Purpose:
To determine the role of qualitative cultures for detecting infection in open tibial fractures.
Methods:
From January 2003 to December 2004, 95 men and 13 women (mean age, 34 years) with open tibial fractures in one or both limbs and without any other sites of infection were prospectively studied. Patients who had been treated with intravenous or oral antibiotics before presentation and/or had undergone debridement or other surgery were excluded.
Results:
Infection was not correlated with age, sex, interval from injury to debridement, and cause of fracture. The association of infection with predebridement cultures was stronger (odds ratio=12.5) than that with postdebridement cultures (odds ratio=4.7).
Conclusion:
Pre- and post-debridement cultures have a role in detecting infection in open tibial fractures. For detecting infection, predebridement cultures have better sensitivity, while postdebridement cultures have better specificity.
