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Updated: Jul 2, 2026

08:49
Models of Bone Metastasis
Published on: September 4, 2012
[Appendicular metastatic involvement in breast cancer]
Arkhiv Patologii
|August 30, 2008
Summary
This case study details appendiceal metastasis from breast cancer in a 60-year-old woman presenting with appendicitis symptoms 18 years post-diagnosis. The findings highlight rare metastatic patterns and inform clinical management strategies.
Area of Science:
- Oncology
- Gastroenterology
Background:
- Breast cancer metastasis can present in unusual locations.
- Appendiceal involvement is a rare manifestation of metastatic breast cancer.
Observation:
- A 60-year-old female patient with a history of breast cancer presented with acute appendicitis symptoms 18 years after primary tumor detection.
- Appendectomy revealed tumor cell infiltration in the muscle layers of the appendix.
- Immunohistochemical analysis showed moderate Estrogen Receptor (Er) and Progesterone Receptor (Pgr) expression, along with positive markers for EMA, K7, K6, and lactoalbumin.
Findings:
- The study confirms appendiceal metastasis as a rare presentation of breast cancer.
- Histopathological and immunohistochemical findings characterize the metastatic infiltrate.
Implications:
- This case expands the understanding of metastatic breast cancer spread.
- Awareness of appendiceal metastasis is crucial for accurate diagnosis and appropriate patient management.

