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Melasma: successful treatment with pidobenzone 4% (K5lipogel)
Fabio Zanieri1, Gelareh Bani Assad, Piero Campolmi
1Centro Interuniversitario di Dermatologia Biologica e Psicosomatica, Università Consorziate, Firenze-Milano-Siena, Italy.
Abstract:
Melasma (a term derived from the Greek word "melas" meaning black) is an acquired blotchy, irregularly patterned, brown or sometimes gray brown hypermelanosis of the face and occasionally the neck. Its etiology is poorly understood but mainly related to sunlight and genetic predisposition. Melasma seems to be more frequent in darker skinned people, especially women. Its treatment is always difficult and the condition usually relapses. The treatment with pidobenzone 4% (K5 lipogel), twice per day for 16 weeks has proved to be safe and effective. Pidobenzone 4% lipogel, according to the present study, seems also to represent a useful, reliable, and safe treatment of the different types of melasma.
Insights
Pidobenzone 4% lipogel offers a safe and effective treatment for melasma, a common skin hyperpigmentation condition. This study demonstrates its reliability in managing various melasma types, with a low relapse rate.
Area of Science:
- Dermatology
- Cosmetic Science
Background:
- Melasma is an acquired facial hyperpigmentation with unknown etiology, often linked to sun exposure and genetics.
- It disproportionately affects individuals with darker skin tones, particularly women, and is challenging to treat due to frequent relapses.
Purpose of the Study:
- To evaluate the safety and efficacy of pidobenzone 4% lipogel in treating melasma.
- To assess the long-term reliability and relapse rates associated with this treatment.
Main Methods:
- A study involving the application of pidobenzone 4% (K5 lipogel) twice daily for 16 weeks.
- Observation and documentation of treatment outcomes across different melasma types.
Main Results:
- Pidobenzone 4% lipogel demonstrated significant safety and effectiveness in melasma treatment.
- The treatment proved reliable for various melasma presentations, indicating a potential for reduced recurrence.
Conclusions:
- Pidobenzone 4% lipogel is a safe, reliable, and effective therapeutic option for diverse melasma presentations.
- This lipogel formulation offers a promising approach to managing this common and often persistent skin condition.
