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Updated: Jul 2, 2026

Bioprospecting of Extremophilic Microorganisms to Address Environmental Pollution
Published on: December 30, 2021
Antibacterial potential of Antarctic lichens against human pathogenic Gram-positive bacteria
Babita Paudel1, Hari Datta Bhattarai, Jin Sung Lee
1Polar BioCenter, Korea Polar Research Institute, KORDI, Songdo Technopark, Songdo-dong 7-50, Yeonsu-gu, Incheon 406-840, South Korea.
Abstract:
Extracts from five Antarctic lichens (L3, Stereocaulon alpinum; L5, Ramalina terebrata; L6, Caloplaca sp.; L8, Lecanora sp.; and L17, Caloplaca regalis) were tested for antimicrobial activities against several clinically important microbes by disk diffusion. The minimum inhibitory concentration (MIC) of each extract was determined by a broth dilution method. Extracts from L3, L5, L6 and L8 were active against two Gram(+) strains. B. subtilis was more sensitive to lichen extracts (except L5) than S. aureus. The MIC of lichen extracts against B. subtilis and S. aureus was observed from 36.7 +/- 0.3 to 953.8 +/- 85.8 microg/mL and 68.5 +/- 0.6 to >1000 microg/mL, respectively. Comparisons of MIC values of Antarctic lichen crude extracts to previously published MIC values of some reported lichen metabolites against Gram(+) bacteria indicated that Antarctic lichens might be an enriched source of effective antibacterial agents against clinically relevant Gram(+) species.
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