[Thrombocytopenic states in the neonatal period]

A total of 316 cases of thrombocytopenic states were analyzed in newborns. The incidence rate of thrombocytopenia among mature infants with varying diseases comprised 37%, hemorrhagic syndrome developed in 23.7% of them. Among the infants admitted to hospital with hemorrhagic syndrome thrombocytopenia was detected almost in half the cases (42%). Most often thrombocytopenia was observed in infections diseases, both intrauterine and postnatal. Transplacental and isoimmune thrombocytopenic purpura comprised 6.3% of all cases, thrombocytopenia caused by amegakaryocytosis--1.5%. Basing on the analysis made three variants of transplacental thrombocytopenic purpura have been distinguished and described. Causes and pathogenesis of thrombocytopenia development in infectious diseases of newborns are discussed.