Keloid formation on palmar surface of hand

Area of Science:

• Dermatology
• Plastic Surgery
• Wound Healing Research

Background:

• Keloids are benign fibroproliferative tumors that arise from scar tissue.
• Palmar skin is generally considered resistant to keloid formation due to its unique biomechanical properties and dense collagen structure.
• Previous literature has suggested an absence of keloid occurrence on the palmar surfaces of the hands.

Observation:

• A case report of a black female patient who developed a large keloid after a surgical procedure on her palm.
• The patient had no prior history of keloid formation.
• The keloid presented as a significant fibroproliferative growth in the palmar region.

Findings:

• This case challenges the established understanding of keloid formation resistance in palmar skin.
• The development of a large keloid post-surgery in this location is unprecedented in English literature.
• Histopathological examination confirmed the nature of the lesion as a keloid.

Implications:

• Suggests that palmar skin may not be entirely immune to keloid development under certain conditions.
• Highlights the need for further investigation into the factors influencing keloid formation in previously resistant anatomical sites.
• This case may inform surgical considerations and patient counseling for procedures involving palmar skin, particularly in predisposed individuals.