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Updated: Jul 2, 2026
Experimental Model of Ligature-Induced Peri-Implantitis in Mice
Published on: May 17, 2024
Immediate implant placement into infected and noninfected extraction sockets: a pilot study
Seok-Woo Chang1, Seung-Yun Shin, Jong-Rak Hong
1Department of Conservative Dentistry, The Institute of Oral Health Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwondong, Gangnamgu, Seoul, Korea.
Objective:
This study compared the osseointegration of immediate implants in dogs in infection-free sites and in sites with periradicular lesions which were removed by simulated periradicular surgery.
Study Design:
Periradicular surgeries were performed to remove intentionally induced periradicular lesions, followed by teeth extraction and immediate implant placement with (experimental group 1) or without (experimental group 2) membranes. In the control group, implants were placed at healthy extraction sockets. After 12 weeks, the animals were killed and the results of histomorphometric study were analyzed by Kruskal-Wallis test.
Results:
Both the control and the experimental implants were clinically acceptable. The control group showed significantly higher bone-implant contact (BIC; 76.03 +/- 7.98%) than the experimental groups 1 (59.55 +/- 14.21%) and 2 (48.62 +/- 20.22%) (P < .05).
Conclusions:
Despite the lower BIC of the experimental groups, this pilot study showed the possibility that immediate implant placement might be successful in extraction sockets with periradicular lesions. Further studies with larger sample sizes are required.