[Acute hepatorenal failure as a component of multiorgan failure syndrome in patients after surgical intervention]

The etiology, pathogenesis, clinical features of acute postoperative hepatorenal failure (APHRF) in 50 surgical patients were studied. APHRF was considered as a component of the multiorgan insufficiency syndrome. The general somatic factors contributing to APHRF development were established: chronic pathology of the liver and kidneys, chronic cardiogenic pathology, hypertension. The risk factors for APHRF development before, at operation and at the nearest period after it were distinguished: shock, hemorrhage, massive transfusion of blood, or its components, hypoxia, systemic arterial hypotension. The attention is attracted to the significance of combination of the systemic arterial hypotension with the contributing general somatic factors and risk factors before, at operation and at the nearest period after it in APHRF development.