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Updated: Jul 2, 2026

An Experimental Paradigm for the Prediction of Post-Operative Pain (PPOP)
Published on: January 27, 2010
[Effect of the local anesthesia in the response to the pain. Study in the inguinal herniotomy]
R M Paredes Esteban1, B Velasco Sánchez, M Martínez
1Servicio de Cirugía Pediátrica del Hospital Universitario Materno-infantil Reina Sofía de Córdoba. rolopa@supercable.es
Insights
Local anesthesia before surgery significantly reduces post-operative pain and metabolic response in pediatric inguinal hemiotomy patients. Age also influences pain behavior, highlighting the importance of tailored anesthetic approaches.
Area of Science:
- Pediatric Surgery
- Anesthesiology
- Pain Management
Context:
- Inguinal hemiotomy is a common pediatric surgical procedure.
- Effective post-operative pain control is crucial for patient recovery.
Purpose:
- To evaluate the efficacy of local anesthesia, in addition to general anesthesia, for controlling post-surgical pain in pediatric patients undergoing inguinal hemiotomy.
Summary:
- A prospective study randomized 60 pediatric patients into three groups: ilio-inguinal nerve blockade before incision, local infiltration after wound closure, or no local anesthetic.
- Pain was assessed using behavioral, biological (arterial tension, heart rate, respiratory frequency), and laboratory (cortisol, prolactin, insulin, glucose) measurements.
- Pre-incision ilio-inguinal blockade (Group I) demonstrated significant reductions in pain behavior, arterial tension, heart rate, respiratory frequency, cortisol, and glucose levels compared to other groups.
Impact:
- Pre-incisional local anesthesia effectively diminishes the metabolic response to surgery and reduces post-operative pain intensity.
- Patient age is a significant factor influencing behavioral responses to pain, alongside anesthetic techniques.
Introduction:
The inguinal hemiotomy is a surgical procedure common in pediatric surgery and as in any operation the control of the pain is fundamental. The aim of this study is to verify the effect of the local anesthesia next to the general anesthesia, in the control of postsurgical pain.
Material And Method:
A prospective study is made in 60 patients submitted for unilateral repair of hernia inguinal and hidrocele, under general anesthesia. The patients were designated at random in three equal groups after the anesthetic induction. In group I ilio-inguinal blockade is made, before the surgical incision. In group II local infiltration is made after the closing of the aponeurosis and in group III the anesthetic is not infiltrate. The age of the patients included was between 1 and 13 years. For the valuation of the pain and comparison between the three groups we used: 1) Measurements of conductual type. 2) Measurements of biological type before and after the intervention: Arterial tension, cardiac frequency, respiratory frequency... 3) Laboratory measurements: cortisol levels, prolactose, insulin and glucose. Two extractions are made, first after the anesthetic induction and second 60 minutes after the intervention. The results were analyzed using computer statistical program SPSS. A probability value of < 0,05 was considered significant.
Results:
1) Conductual measurements: the differences between groups I and II in relation to the III were significant. This conductual difference also was related to the age of the patients. 2) Measurements of biological type: in groups I and II the postoperative arterial tension average was smaller, but only in group I the difference was significant. The heart rate decreased in the three groups, but was significant only in group I, like the respiratory frequency. 3) Laboratory measurements: in groups I and II the levels of cortisol and glucose diminished in the postoperative period, but only in group I the difference was significant. The values of prolactose diminished in the postoperative period in group I but was not significant. Insulin experienced an increase in the three groups, although smaller in group I.
Conclusions:
1) The results of the study demonstrate specially that the local infiltration of anesthetic diminishes the metabolic answer and reduces the intensity of the postoperating pain, when is made before the beginning of the surgery. 2) In the conductual answer to the pain not only influences the use of the anesthetics but the age of the patient.
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