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Updated: Jul 2, 2026

Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
Minimally invasive surgical approaches and management of prostate cancer
Mark L Gonzalgo1, Nilesh Patil, Li-Ming Su
1Department of Urology, James Buchanan Brady Urological Institute, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Marburg 145, Baltimore, MD 21287, USA.
Abstract:
For clinically localized prostate cancer, radical prostatectomy remains the "gold standard" treatment. New forms of minimally invasive therapies are sought out by patients, however, because of the potential morbidity associated with open surgery. With quality-of-life aspects influencing patient decision making, minimally invasive therapeutic modalities have generated great interest among patients. Laparoscopic radical prostatectomy, robotic-assisted laparoscopic prostatectomy, brachytherapy, cryotherapy, and high-intensity focused ultrasound are all considered to be minimally invasive treatment options for the management of clinically localized prostate cancer.
Insights
Radical prostatectomy is the standard for localized prostate cancer. Minimally invasive therapies like laparoscopic surgery, brachytherapy, and cryotherapy are gaining interest due to reduced morbidity and improved quality of life.
Area of Science:
- Urology
- Surgical Oncology
Background:
- Radical prostatectomy is the established treatment for localized prostate cancer.
- Patients increasingly seek minimally invasive options due to concerns about surgical morbidity.
- Quality of life is a significant factor in treatment decisions for prostate cancer.
Purpose of the Study:
- To review minimally invasive therapeutic modalities for clinically localized prostate cancer.
- To highlight patient interest in less invasive treatment options.
Main Methods:
- Review of current literature on minimally invasive prostate cancer treatments.
- Identification of various minimally invasive techniques available.
Main Results:
- Several minimally invasive options exist for localized prostate cancer management.
- These include laparoscopic radical prostatectomy, robotic-assisted laparoscopic prostatectomy, brachytherapy, cryotherapy, and high-intensity focused ultrasound.
Conclusions:
- Minimally invasive therapies offer alternatives to traditional open surgery for prostate cancer.
- These approaches address patient demand for treatments with potentially lower morbidity and better quality of life outcomes.
