Related Experiment Video
Updated: Jul 2, 2026

Generating Acute and Chronic Experimental Models of Motor Tic Expression in Rats
Published on: May 27, 2021
[Tourette syndrome. Genetics, neuroanatomy and neurotransmitters]
Nanette M M Mol Debes1, Liselotte Skov, Helle Hjalgrim
1Glostrup Hospital, Børneafdeling L, Glostrup. nanettemol@hotmail.com
Abstract:
The etiology and pathophysiology of Tourette syndrome (TS) have not yet been clarified. Despite inconsistencies in the literature, some conclusions can be drawn on genetics, neuroanatomy and neurotransmitters. The inheritance of TS is unknown; the etiology seems to be polygenic. The basal ganglia are probably smaller in patients with TS. A dysfunction in the dopaminergic pathway causes tics. ADHD results from a decreased concentration of dopamine and an increased concentration of noradrenaline. OCD is caused by a dysfunction in serotonin and probably dopamine.
Related Concept Videos
Disorders of the Nervous Tissue
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
Human Genetics
The complex relationship between genetics and psychology is observable through common biological components such...
Parkinson Disease ll: Pathophysiology
Excitatory and Inhibitory Effects of Neurotransmitters
Drugs Affecting Neurotransmitter Synthesis
Alterations in Muscle Tone ll

