Egg drop syndrome 1976 (EDS-76) virus infection in inadequately vaccinated chickens

Experiments were carried out to study the epizootiology of the egg drop syndrome 1976 virus infection in chickens that were not adequately protected by vaccination. Virus excretion was demonstrated when chickens vaccinated at the recommended level were challenged within 10 days of vaccination and when chickens were challenged 6 weeks after administration of low doses of vaccine. In the latter experiment, those chickens which shed virus had all shown a poor haemagglutination inhibition antibody response to vaccination but had high serum neutralisation antibody titres when challenged.