The importance of parent artery geometry in intra-aneurysmal hemodynamics

We show the importance of arterial geometry in intra-aneurysmal hemodynamics. Using a new geometric parameterized saccular aneurysm model including parameters for parent artery shape and the configuration of the aneurysm in the parent artery, we performed a parametric computational fluid dynamics study. We examined lateral saccular aneurysm models with different aneurysm shapes (i.e., the ratio of aneurysm height to aneurysm neck diameter) and different configurations (i.e., the torsion angle of the aneurysm to the upstream part of the parent artery). The aneurysm lateral to the curve of the parent artery had significantly higher wall shear stress than the aneurysm inside or outside the curve of the artery, even with the same shape of the aneurysm. Our findings suggest the important role played by the configuration of the aneurysm relative to the parent artery in intra-aneurysmal hemodynamics.