Related Experiment Video
Updated: Sep 17, 2026

Method and Instrumented Fixture for Femoral Fracture Testing in a Sideways Fall-on-the-Hip Position
Published on: August 17, 2017
Loading Effects: Geometry versus Intrinsic Forces in Injury Risk Assessment of the Femur in Children with
Maeve M McDonald1, Gerald F Harris2, Joseph LeSueur3
1Department of Orthopaedic Surgery, Medical College of Wisconsin, 8701 W Wisconsin Ave, Milwaukee, Wisconsin, 53226, United States.
Abstract:
Osteogenesis imperfecta (OI) is a rare genetic disorder but is the most common disorder of bone etiology with little known about the impact of physiologic factors on fracture risk. Finite element analysis (FE) models of OI bone have been previously developed to examine fracture risk during ambulation and various daily activities of the femur and tibia. This study aims to further investigate the impact of long bone deformity and muscle activation forces in children and adolescents with OI. Pediatric femoral FE models of normal, OI type I, and OI type III bone material properties assessed effects of lateral bowing versus increased gluteus medius and gluteus maximus force production on bone injury risk. Models incorporating increased lateral bowing and muscle forces showed up to 7.56% higher stress levels than the standard model with no bowing and normal muscle forces, with muscle forces having a greater impact than lateral bowing. This study provides quantitative information to help establish methodology for FE analysis to assess femoral fracture risk in individuals with OI.
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Impact Loading
In cases of elastic deformation,...
Bones of the Lower Limb: Femur and Patella
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Relation between Poisson's ratio, Modulus of Elasticity and Modulus of Rigidity

