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Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers
Published on: January 9, 2026
[Going from the tube feeding to the oral feeding in infants]
1CESAP formation, 5 rue Blanche, 75009 Paris, France. senez.catherine@wanadoo.fr
Insights
Preparing infants for oral feeding early during hospitalization can help ensure a successful transition from tube feeding. This approach supports infant development and eases the transition home for families.
Area of Science:
- Neonatology
- Pediatric Gastroenterology
- Infant Nutrition
Context:
- Tube feeding is a critical intervention in neonatal care, improving survival rates.
- Prolonged tube feeding can complicate the transition to oral feeding.
- Home-going with tube feeding presents significant challenges for parents.
Purpose:
- To outline a strategy for preparing infants for oral feeding early in hospitalization.
- To facilitate a successful transition from tube to oral feeding and support home discharge.
- To prevent the need for harmful feeding methods by introducing oral stimulation.
Summary:
- This study proposes an integrated approach to tube feeding management in neonates.
- It involves early oral cavity stimulation with palatable substances and cup feeding methods.
- The strategy aims to mimic natural feeding rhythms and physiological digestive processes.
Impact:
- Enables earlier and smoother transition to oral feeding for infants.
- Reduces parental stress associated with tube feeding at home.
- Promotes better digestive adaptation by respecting the oral-to-intestinal pathway.
Abstract:
Tube feeding has greatly improved the vital prognosis in neonatology. However, after a varying time of tube feeding, the return to oral feeding can present quite a challenge for some infants. Moreover, going back home with tube feeding can cause succession of ordeals for the parents. Our purpose is to work out a successful return to home by having prepared the infant for future oral feeding at the very beginning of the hospitalization. Going from minor to serious pathologies, we describe a method aimed at helping the infant's sucking and an alternative method of cup feeding; both intended to avoid a very harmful forced feeding. We have to organize tube feeding, while inuring the mouth to tasty stimulations, and establishing a frequency comparable to the normal feeding rhythm. The intolerance to a bolus of food or rapid flow rate occur when the oral cavity and the oesophagus are bypassed by the tube. The digestive physiology requires observing the digestive chain reaction going from the mouth to the small intestine.
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