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Depolarizing Blockers: Pharmocokinetics

Depolarizing Blockers: Pharmocokinetics

Depolarizing blockers are administered through intravenous injection. Succinylcholine is the most common choice of depolarizing blockers in emergency clinical practices. Although they have a rapid onset, they readily diffuse away from the motor end plate into the extracellular fluid. They are metabolized by enzymes such as liver butyrylcholinesterase and plasma pseudocholinesterases. This produces a short duration of action, typically 5-10 minutes long, unlike nondepolarizing blockers, which...

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Enhanced Sample Multiplexing of Tissues Using Combined Precursor Isotopic Labeling and Isobaric Tagging cPILOT

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Whatever happened to Pittsburgh Compound-A?

William E Klunk¹, Chester A Mathis

¹Department of Psychiatry and Neurology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Alzheimer Disease and Associated Disorders

|September 5, 2008

Summary

No abstract available in PubMed .

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