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Updated: Jul 2, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
Antimicrobial stewardship in institutions and office practices
1Ankur Institute of Child Health, Smt NHL Mun Medical College, Ahmedabad, India. rajucshah@rediffmail.com
Antimicrobial stewardship programs are crucial for preserving antibiotic effectiveness by promoting appropriate use. Increasing medical professional awareness and integrating technology can combat antimicrobial overuse and improve patient outcomes.
Area of Science:
- Infectious Diseases
- Public Health
- Health Services Research
Background:
- Medically inappropriate, ineffective, and economically inefficient antimicrobial use is prevalent globally, particularly in developing nations.
- Antimicrobial resistance poses a significant threat to public health, necessitating strategies to preserve the efficacy of these vital medications.
- Existing healthcare systems face challenges in optimizing antimicrobial prescribing practices.
Purpose of the Study:
- To highlight the importance and components of comprehensive, evidence-based antimicrobial stewardship programs.
- To emphasize the need for increased awareness and discipline in antimicrobial prescribing among medical professionals.
- To explore the potential of advanced information technology in enhancing antimicrobial stewardship.
Main Methods:
- Review of current antimicrobial use and resistance patterns.
- Analysis of essential elements for effective antimicrobial stewardship programs.
- Assessment of the role of medical professional education and technological integration.
Main Results:
- Effective stewardship requires tailoring programs to local antimicrobial use, resistance issues, and available resources.
- Increased awareness and disciplined prescribing by medical professionals are vital for program success.
- Information technology integration shows promise in reducing antimicrobial overuse and improving clinical outcomes.
Conclusions:
- Comprehensive antimicrobial stewardship programs are essential to combat antimicrobial resistance and ensure drug efficacy.
- Education, resource-appropriate strategies, and technological advancements are key to successful antimicrobial stewardship.
- Physicians must carefully weigh the benefits against risks and justify empirical antibiotic prescriptions.
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