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Flow Cytometry

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
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Related Experiment Video

Updated: Jul 2, 2026

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells

Published on: March 24, 2023

Quality control in phenotypic analysis by flow cytometry.

¹Comprehensive Cytometric Consulting, Ballwin, Missouri, USA.

Current Protocols in Cytometry

|September 5, 2008

Summary

This summary is machine-generated.

A daily quality control program is proposed to ensure laboratory instrument reliability and accurate test results, even with limited resources. This approach enhances diagnostic accuracy and operational efficiency.

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Last Updated: Jul 2, 2026

Simultaneous Assessment of Kinship, Division Number, and Phenotype via Flow Cytometry for Hematopoietic Stem and Progenitor Cells

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Published on: March 24, 2023

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Quality-Controlled Sputum Analysis by Flow Cytometry

Quality-Controlled Sputum Analysis by Flow Cytometry

Published on: August 9, 2021

Area of Science:

Clinical Chemistry
Laboratory Medicine
Quality Management

Background:

Ensuring the reliability and accuracy of laboratory instruments is critical for patient diagnosis and treatment.
Current operational constraints often challenge the implementation of comprehensive quality control measures.

Purpose of the Study:

To propose a specific daily quality control (QC) program.
To ensure consistent instrument reliability and accurate results.
To address QC within existing resource limitations.

Main Methods:

Development of a targeted daily QC protocol.
Integration of QC procedures into routine laboratory workflow.
Focus on essential QC metrics for key analytical processes.

Main Results:

The proposed program provides a framework for daily monitoring of instrument performance.
It aims to detect deviations promptly, minimizing the impact on patient results.
The program is designed for practical implementation under typical laboratory constraints.

Conclusions:

A structured daily QC program is feasible and essential for maintaining high-quality laboratory services.
Implementing this program can enhance diagnostic accuracy and operational efficiency.
This approach supports reliable patient care despite resource limitations.