Related Experiment Video
Updated: Jul 2, 2026

Array Comparative Genomic Hybridization (Array CGH) for Detection of Genomic Copy Number Variants
Published on: February 21, 2015
Comparative genomic hybridization (CGH)--detection of unbalanced genetic aberrations using conventional and
E Schröck1, Z Weaver, D Albertson
1Institute of Genetic Medicine, Charité, Berlin, Germany.
Abstract:
This unit presents comparative genomic hybridization (CGH), a genome-wide screening technique for genetic aberrations in tumor samples. Specific emphasis is placed on recent applications to the analysis of murine model systems for human cancer. CGH is an invaluable tool for identifying the characteristic genetic rearrangements in these models. The authors discuss an exciting new method currently being developed, array CGH, which results in a tremendous increase in resolution. Oncogene amplifications and deletions of tumor-suppressor genes are detected on a single-gene level. Detailed protocols are supplied for CGH analysis of both human and mouse chromosomes.
More Related Videos
16:37Technical Demonstration of Whole Genome Array Comparative Genomic Hybridization
Published on: August 5, 2008
09:32An Array-based Comparative Genomic Hybridization Platform for Efficient Detection of Copy Number Variations in Fast Neutron-induced Medicago truncatula Mutants
Published on: November 8, 2017
Related Concept Videos
DNA Microarrays
Karyotyping