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Painful subacute thyroiditis in Hawaii
R A Nordyke1, F I Gilbert, C Lew
1Department of Nuclear Medicine, Straub Clinic & Hospital, Honolulu, Hawaii.
The Western Journal of Medicine
|July 11, 1991
Summary
Subacute thyroiditis predominantly affects middle-aged women and often presents bilaterally. A characteristic pain-free interval can delay diagnosis, potentially mimicking other thyroid conditions like cancer.
Area of Science:
- Endocrinology
- Thyroidology
- Clinical Medicine
Background:
- Subacute thyroiditis is an inflammatory thyroid condition.
- Understanding its natural history is crucial for accurate diagnosis and management.
- Demographic and clinical features require further elucidation.
Purpose of the Study:
- To prospectively investigate the demographic characteristics of subacute thyroiditis.
- To determine the seasonality and natural course of the disease.
- To identify potential diagnostic challenges.
Main Methods:
- Prospective study of 269 patients diagnosed with painful subacute thyroiditis.
- Data collection included patient demographics, disease presentation, and duration of symptoms.
- Analysis of clinical findings over a 22-year period (1960-1982).
Main Results:
- The mean patient age was 37.1 years, with a female to male ratio of 6.7:1.
- Bilateral involvement was observed in 69% of patients at initial presentation.
- A mean duration of thyroid tenderness was 2.2 months, followed by a 2.8-month period of palpable lumps, creating a diagnostic "window".
Conclusions:
- Subacute thyroiditis exhibits distinct demographic patterns, primarily affecting women.
- The disease course includes a significant interval between symptom resolution and lump disappearance.
- This pain-free period poses a diagnostic challenge, increasing the risk of misdiagnosis, particularly with thyroid cancer.
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