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In vivo Structural Assessments of Ocular Disease in Rodent Models using Optical Coherence Tomography
Published on: July 24, 2020
[Ocular ochronosis. A case report]
N Ben Rayana1, N Chahed, S Khochtali
1Service d'Ophtalmologie, Centre Hospitalo-Universitaire Farhat Hached, Sousse, Tunisie. narjesbenrayana@yahoo.fr
Abstract:
Ochronosis or alkaptonuria is a rare inherited disease. It is characterized by the deposition of dark pigments in collagen-rich tissues, which leads to clinical manifestations such as arthropathy. The ochronotic pigment can be found in the sclera, the conjunctiva, and the limbic cornea. Vision is usually not affected. We report the case of 47-year-old patient who complained of lower back pain. Ophthalmologic examination showed dark pigments in the conjunctiva. The increased levels of homogentisic acid in urine confirmed the diagnosis of ochronosis.
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