Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches01:23

Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches

Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Relative Risk01:12

Relative Risk

Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
Receiver Operating Characteristic Plot01:15

Receiver Operating Characteristic Plot

A ROC (Receiver Operating Characteristic) plot is a graphical tool used to assess the performance of a binary classification model by illustrating the trade-off between sensitivity (true positive rate) and specificity (false positive rate). By plotting sensitivity against 1 - specificity across various threshold settings, the ROC curve shows how well the model distinguishes between classes, with a curve closer to the top-left corner indicating a more accurate model. The area under the ROC curve...
Hazard Ratio01:12

Hazard Ratio

The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial evaluating a...
Sensitivity, Specificity, and Predicted Value01:13

Sensitivity, Specificity, and Predicted Value

In healthcare diagnostics, laboratory tests play a crucial role in identifying and diagnosing a wide range of medical conditions. However, interpreting test results is not always straightforward. An abnormal test result does not always confirm the presence of a disease, just as a normal result does not guarantee its absence. To assess the reliability of these diagnostic tools, healthcare practitioners rely on two key statistical indicators: sensitivity and specificity.
Sensitivity is the...
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT01:25

Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT

Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Daily Nutrient Intake and Inflammation Among US Adults.

Journal of the American Board of Family Medicine : JABFM·2026
Same author

Design and Recruitment for the Comparative Effectiveness of Zolpidem/Trazodone and Cognitive Behavioral Therapy for Insomnia (COZI) Study in Rural Adults.

Behavioral sleep medicine·2026
Same author

Acceptability of an adolescent lifestyle mHealth app: a qualitative study using focus groups and interviews.

mHealth·2026
Same author

Qualitative User-Centered Design: Programming Changes in a Self-Management Blood Pressure Application.

Applied clinical informatics·2026
Same author

Economic Burden of Long COVID: Lost Labor Costs in US Adults.

Journal of the American Board of Family Medicine : JABFM·2026
Same author

Patient trust in the health system, Internet information searching and the patient-provider relationship.

Frontiers in medicine·2025

Related Experiment Video

Updated: Jul 2, 2026

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

Evaluating multivariate risk scores for clinical decision making.

Richelle J Koopman1, Arch G Mainous

  • 1Department of Family and Community Medicine, University of Missouri-Columbia, Columbia, MO 65212, USA. koopmanr@health.missouri.edu

Family Medicine
|September 9, 2008
PubMed
Summary
This summary is machine-generated.

Clinicians should carefully consider the development, validation, and limitations of disease risk scores. Understanding these factors optimizes clinical decision-making and patient care.

Related Experiment Videos

Last Updated: Jul 2, 2026

An R-Based Landscape Validation of a Competing Risk Model
05:37

An R-Based Landscape Validation of a Competing Risk Model

Published on: September 16, 2022

Area of Science:

  • Clinical Medicine
  • Medical Informatics

Background:

  • Medical literature features numerous disease risk scores.
  • Risk scores simplify complex multifactorial disease prediction.

Purpose of the Study:

  • To highlight the importance of understanding risk score development and limitations.
  • To guide clinicians in optimizing the use of risk assessment tools.

Main Methods:

  • Review of existing literature on clinical risk scores.
  • Analysis of factors influencing risk score utility and application.

Main Results:

  • Risk scores synthesize multiple risk factors for easier analysis.
  • Effective use requires considering patient populations, included factors, and workflow integration.

Conclusions:

  • Awareness of risk score strengths and weaknesses is crucial for clinical decision-making.
  • Risk assessment tools are likely to increase in importance with electronic health record adoption.