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Related Experiment Video

Updated: Jul 2, 2026

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting

Rapid Fractionation and Isolation of Whole Blood Components in Samples Obtained from a Community-based Setting

Published on: November 30, 2015

Blood components produced from whole blood using the Atreus processing system.

Stephen Thomas¹, Martin Beard, Margaret Garwood

¹Components Development Laboratory, NHS Blood & Transplant, Brentwood, UK. stephen.thomas@nbs.nhs.uk.

|September 9, 2008

Summary

The Atreus 2C+ system effectively processes whole blood into quality red blood cells, fresh-frozen plasma, and buffy coats. Active cooling of whole blood before processing showed no significant impact on component quality for clinical use.

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Area of Science:

Transfusion Medicine
Blood Component Processing
Hematology

Background:

The Atreus 2C+ system automates whole blood processing.
This study investigated the impact of active cooling on component quality.

Purpose of the Study:

To compare the quality of blood components (RBCs, FFP, BCs) from whole blood stored with or without active cooling.
To assess the suitability of Atreus-processed components for clinical use.

Main Methods:

Whole blood was processed using the Atreus 2C+ system after storage (14-18 hours) with or without active cooling.
Red blood cell quality markers were tested up to Day 42.
Plasma and buffy coat quality were assessed.

Main Results:

All red blood cells met UK specifications; no quality differences were observed between cooled and uncooled whole blood.
Fresh-frozen plasma met all UK specifications, with no differences based on cooling.
Buffy coat hematocrit was lower from uncooled whole blood, but activation levels were similar.

Conclusions:

Blood components processed by the Atreus system are suitable for clinical use.
There is no clinically significant difference in component quality whether whole blood is actively cooled or not prior to processing.