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Updated: Jul 1, 2026

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Polymerase Chain Reaction: Basic Protocol Plus Troubleshooting and Optimization Strategies
Published on: May 22, 2012
Enhanced amplification of polymerase chain reaction by addition of cosolutes derived from a cellular compatible
Kazuya Koumoto1, Hirofumi Ochiai, Naoki Sugimoto
1FIBER, Konan University, Higashinada-ku, Kobe, 658-8501, Japan.
Nucleic Acids Symposium Series (2004)
|September 9, 2008
Abstract:
We designed and synthesized artificial compatible solutes which can not only decrease the melting temperature of DNA duplexes dependent of their chemical structures but also improve the amplification of highly stable genome DNA sequence.
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