Synthesis and antiviral evaluation of 4-fluoropyrazole-3-carboxamide nucleoside derivatives
Frederic Leroy1, Dominique Chaves, David Dukhan
1Idenix Pharmaceuticals, Medicinal Chemistry Laboratory, Cap Gamma, 1682 Rue de la Valsière, 34189 Montpellier Cedex 4, France. leroy.frederic@idenix.com
Abstract:
A series of novel 4-fluoro-1H-pyrazole-3-carboxamide nucleoside analogues were synthesized and evaluated as potential inhibitors of RNA virus replication, including hepatitis C virus (HCV).
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