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Related Experiment Video

Updated: Jul 1, 2026

A 3D Quantification Technique for Liver Fat Fraction Distribution Analysis Using Dixon Magnetic Resonance Imaging

A 3D Quantification Technique for Liver Fat Fraction Distribution Analysis Using Dixon Magnetic Resonance Imaging

Published on: October 20, 2023

Dixon techniques for water and fat imaging.

¹Department of Imaging Physics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA. jma@di.mdacc.tmc.edu

Journal of Magnetic Resonance Imaging : JMRI

|September 9, 2008

Summary

Dixon imaging technique separates water and fat signals using two spin echo images. This method enables fat suppression and direct water-fat quantitation in magnetic resonance imaging (MRI).

Area of Science:

Medical Imaging
Spectroscopic Imaging
Magnetic Resonance Imaging (MRI)

Background:

The Dixon technique, introduced in 1984, is a spectroscopic imaging method for separating water and fat signals.
It utilizes a modified spin echo pulse sequence to acquire two distinct images.

Purpose of the Study:

To review the physical principles underlying Dixon imaging techniques.
To describe major technical advancements in Dixon imaging over the past two decades.
To highlight applications such as fat suppression and water-fat quantitation in MRI.

Main Methods:

Acquisition of two spin echo images: one in-phase and one 180 degrees out-of-phase for water and fat signals.
Generation of separate water-only and fat-only images from the acquired data.

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Exploration of techniques to enhance insensitivity to magnetic field inhomogeneity.

Main Results:

Successful generation of water-only and fat-only images.
Demonstrated utility of water-only images for fat suppression in clinical MRI.
Enabled direct, image-based quantitation of water and fat.

Conclusions:

The Dixon technique provides valuable water-only and fat-only images for MRI.
It facilitates both fat suppression and accurate water-fat quantitation.
Ongoing research has significantly improved the original Dixon method, enhancing its clinical applicability.