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Coupled rolling circle amplification loop-mediated amplification for rapid detection of short DNA sequences

Jennifer Marciniak1, Andrew Kummel, Sadik Esener

  • 1Department of Bioengineering, University of California-San Diego, La Jolla, CA, USA.

Biotechniques
|September 10, 2008
PubMed
Summary

Circularizable oligonucleotide probes detect DNA with single-base precision. A novel amplification method combining rolling circle amplification and loop-mediated amplification offers rapid, sensitive DNA detection.

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