Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety and Biodistribution of Topical Laquinimod, an Immunomodulator Targeting Aryl Hydrocarbon Receptor: The LION Study.

Ophthalmology science·2026
Same author

A Simplified Classification for Age-Related Macular Degeneration Based on Optical Coherence Tomography.

Ophthalmic surgery, lasers & imaging retina·2026
Same author

Predictors of Good Visual Recovery in Patients With Spontaneously Resolved Acute CSCR - MICRoN Report Number Thirteen.

American journal of ophthalmology·2026
Same author

Comparison between thin and thick choroid eyes in central serous chorioretinopathy.

Retina (Philadelphia, Pa.)·2026
Same author

A Simplified Classification for Age-Related Macular Degeneration Based on Optical Coherence Tomography.

medRxiv : the preprint server for health sciences·2026
Same author

Regression of a Subretinal Proliferation Band with Intravitreal Methotrexate in Recurrent Retinal Detachment: A Case Report.

Retinal cases & brief reports·2026

Related Experiment Video

Updated: Jul 1, 2026

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery
04:36

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Published on: April 14, 2026

Port geometry and its influence on vitrectomy.

Charles DeBoer1, Sophia Fang, Luiz H Lima

  • 1Department of Ophthalmology, Keck School of Medicine, University of Southern California, USA.

Retina (Philadelphia, Pa.)
|September 10, 2008
PubMed
Summary
This summary is machine-generated.

Vitreous cutter port size impacts flow rates, with larger ports offering diminishing returns. Novel cutter tip designs affect tissue interaction, suggesting specialized instruments for specific surgical tasks.

More Related Videos

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Related Experiment Videos

Last Updated: Jul 1, 2026

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery
04:36

Implantation Protocol of the Foldable Capsular Vitreous Body for Complex Vitreoretinal Surgery

Published on: April 14, 2026

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases
11:20

Retinal Pigment Epithelium Transplantation in a Non-human Primate Model for Degenerative Retinal Diseases

Published on: June 14, 2021

Area of Science:

  • Ophthalmology
  • Surgical Instrumentation
  • Biomedical Engineering

Background:

  • Vitreous cutters are essential tools in ophthalmic surgery.
  • Optimizing flow rates and tissue interaction is crucial for surgical efficiency and patient outcomes.

Purpose of the Study:

  • To investigate how vitreous cutter port geometry influences fluid dynamics.
  • To evaluate novel vitreous cutter tips designed for specific surgical applications.

Main Methods:

  • Custom 20-gauge and 25-gauge vitreous cutter tips with varied port sizes were tested.
  • Evaluations included porcine vitreous and water flow rates, retinal cutting vacuum, lens cutting/aspiration time, and in-situ surgical assessment.

Main Results:

  • Both water and vitreous flow rates increased with port diameter, reaching a plateau.
  • Some tips enhanced water removal, but none surpassed the control for vitreous or lens removal.
  • Several novel tips required higher vacuum levels for retinal cutting compared to the standard tip.

Conclusions:

  • Larger port diameters yield diminishing flow rate improvements in vitreous cutters.
  • Vitreous cutter port modifications significantly alter surgical tissue interactions.
  • Future developments may involve combinational or surgery-specific instruments for optimized port selection.