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Predictors of Good Visual Recovery in Patients With Spontaneously Resolved Acute CSCR - MICRoN Report Number Thirteen
Nasiq Hasan1, Niroj Sahoo1, Korrina Gidwani1
1From the University of Pittsburgh School of Medicine (N.H., N.S., K.G., G.G., J.C.), Pittsburgh, Pennsylvania, USA.
American Journal of Ophthalmology
|May 21, 2026
Summary
Older age, poorer baseline vision, absence of serous pigment epithelial detachment, and bilateral disease predict poor visual outcomes in acute central serous chorioretinopathy (CSCR) patients after spontaneous resolution.
Area of Science:
- Ophthalmology
- Retinal Diseases
- Choroidal Disorders
Background:
- Central serous chorioretinopathy (CSCR) is a condition affecting vision, often resolving spontaneously.
- However, not all patients achieve optimal visual acuity (VA) after resolution.
Purpose of the Study:
- To identify factors predicting failure to achieve 20/20 visual acuity (VA) in patients with spontaneously resolved acute CSCR.
- To establish baseline biomarkers for prognostication in CSCR.
Main Methods:
- A multicenter retrospective observational cohort study involving 189 patients with first-episode, spontaneously resolved acute CSCR.
- Patients were classified by post-resolution best-recorded visual acuity (BRVA) as ≥20/20 or <20/20.
- Demographic data and multimodal imaging features were analyzed using multivariate logistic regression.
Main Results:
- Of 195 eyes, 55.38% achieved ≥20/20 VA, while 44.62% had <20/20 VA.
- Independent predictors for <20/20 VA included older age (OR=1.07), poorer baseline VA (OR=1.37), absence of serous pigment epithelial detachment (PED) (OR=0.30), and bilaterality (OR=4.12).
Conclusions:
- Spontaneous resolution of subretinal fluid (SRF) in acute CSCR does not guarantee 20/20 vision.
- Older age, worse baseline vision, lack of serous PED, and bilateral disease are key predictors of suboptimal visual outcomes.
- These findings aid in prognostication and functional assessment for acute CSCR cases.
