Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Herpes

Herpes

Herpes simplex type 1 (HSV‑1) is a widespread pathogen responsible for orolabial lesions. It is an enveloped, double-stranded DNA (dsDNA) virus belonging to the family Herpesviridae. Once the virus infects a host cell, its double‑stranded DNA genome is delivered into the nucleus, where a coordinated cascade of immediate‑early, early, and late gene expression directs viral DNA replication, structural protein synthesis, and virion assembly. After primary infection of epithelial cells, HSV-1...

Genital Herpes

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.

Chickenpox

Chickenpox

Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...

Cytomegalovirus Disease

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Engineered Norovirus-Derived Nanoparticles as a Plug-and-Play Cancer Vaccine Platform.

ACS nano·2023

Same author

A Medical Image Segmentation Method Based on Improved UNet 3+ Network.

Diagnostics (Basel, Switzerland)·2023

Same author

Role of crescents for lupus nephritis in clinical, pathological and prognosis: a single-center retrospective cohort study.

European journal of medical research·2023

Same author

Stage II Pancreatic Adenocarcinoma after Endovascular Repair of Abdominal Aortic Aneurysm: A Case Report and Literature Review.

Journal of clinical medicine·2023

Same author

Local changes in snow depth dominate the evolving pattern of elevation-dependent warming on the Tibetan Plateau.

Science bulletin·2023

Same author

Dendrobium officinale polysaccharide prevents neuronal apoptosis via TET2-dependent DNA demethylation in high-fat diet-induced diabetic mice.

International journal of biological macromolecules·2023

Search research articles

Related Experiment Video

Updated: Jul 1, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

[Herpes associated erythema multiforme: a case report].

Qing-fu Li¹, Duo Li, Hong-mei Zhou

¹Dept. of Oral Medicine, West China College of Stomatology, Sichuan University, Chengdu 610041, China.

Hua Xi Kou Qiang Yi Xue Za Zhi = Huaxi Kouqiang Yixue Zazhi = West China Journal of Stomatology

|September 11, 2008

Summary

Herpes associated erythema multiforme (HAEM) is a recurrent skin condition triggered by herpes simplex virus, marked by increased CD4+ T cells. This case review explores HAEM mechanisms, diagnosis, and treatment.

Related Experiment Videos

Last Updated: Jul 1, 2026

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Ex Vivo Infection of Murine Epidermis with Herpes Simplex Virus Type 1

Published on: August 24, 2015

Area of Science:

Dermatology
Virology
Immunology

Background:

Herpes associated erythema multiforme (HAEM) is an acute, exudative skin and mucosal disease.
It is triggered by the herpes simplex virus and characterized by recurrence.

Observation:

The condition involves an increase in CD4+ T lymphocytes.
This case report details a specific instance of HAEM.

Findings:

The study reviews the potential mechanisms underlying HAEM.
Diagnostic criteria, therapeutic strategies, and prognostic factors are discussed.

Implications:

Understanding HAEM pathogenesis can lead to improved treatment protocols.
This review aids clinicians in managing recurrent HAEM cases.