Related Experiment Video
Updated: Jul 1, 2026

Experimental Demyelination and Remyelination of Murine Spinal Cord by Focal Injection of Lysolecithin
Published on: March 26, 2015
Recurrent monofocal demyelinating disease
P Jung1, M Strittmatter, H Steinmetz
1Department of Neurology, Johann Wolfgang Goethe-University, Schleusenweg 2-16, D-60528 Frankfurt am Main, Germany. Patrick.Jung@em.uni-frankfurt.de
Abstract:
We describe a patient with recurrent brainstem symptoms and migraine-like headache. Magnetic resonance imaging (MRI) showed a symptomatic hyperintense T2-weighted lesion in the middle cerebellar peduncle and the trigeminal nuclei and an asymptomatic periventricular lesion of Dawson finger shape. The findings were suspicious for a first demyelinating event, possibly representing the first manifestation of multiple sclerosis (MS). Nevertheless, this case report also illustrates several pitfalls in the differential diagnosis of MS.
Related Concept Videos
Multiple Sclerosis l: Introduction
Cytomegalovirus Disease
Poliomyelitis
Encephalitis ll: Pathophysiology
Encephalitis l: Introduction
