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Perioperative type I aortic dissection during conventional coronary artery bypass surgery: risk factors and
Bulend Ketenci1, Yavuz Enc, Batuhan Ozay
1Siyami Ersek Thoracic and Cardiovascular Surgery Centre, Istanbul, Turkey. bulendketenci@gmail.com
Insights
Perioperative iatrogenic type I aortic dissection (PIAD) is a rare complication of coronary artery bypass surgery. Risk factors include female sex, hypertension, peripheral arterial disease, wider aortic diameter, and high cardiopulmonary bypass pressure.
Area of Science:
- Cardiovascular Surgery
- Thoracic Surgery
- Vascular Surgery
Background:
- Perioperative iatrogenic type I aortic dissection (PIAD) is a rare but potentially fatal complication of conventional coronary artery bypass surgery (CCABG).
- Prompt recognition and repair of PIAD are crucial for improving patient outcomes.
Purpose of the Study:
- To identify risk factors and outcomes associated with PIAD following CCABG.
- To compare characteristics of patients with PIAD to a control group without PIAD.
Main Methods:
- Retrospective review of hospital records for patients undergoing CCABG between January 2001 and June 2007.
- Identified 21 patients with PIAD (0.20%) out of 10,130 CCABG procedures.
- Compared demographic, clinical, and intraoperative variables between PIAD patients and a control group (n=603).
Main Results:
- PIAD occurred intraoperatively in 90% of cases, often after aortic crossclamp removal.
- Significant differences between PIAD and control groups included sex (P=.05), history of hypertension (P=.001), and peripheral arterial disease (PAD) (P=.001).
- Wider aortic diameter (P=.019) and high cardiopulmonary bypass pressure (P=.0001) were associated with PIAD. Mortality was high (33.3% preoperatively, 14.2% postoperatively).
Conclusions:
- PIAD following CCABG is associated with a high mortality rate.
- Identified risk factors for PIAD include female sex, history of PAD and hypertension, increased aortic diameter, and high cardiopulmonary bypass pressure.
- Early detection and management are critical for improving survival rates in patients experiencing PIAD.
Objectives:
Perioperative iatrogenic type I aortic dissection (PIAD) is a rare but potentially fatal complication of conventional coronary artery bypass surgery (CCABG). Prompt recognition and repair of PIAD may significantly improve outcomes.
Methods:
We reviewed the hospital records of patients with PIAD occurring as a complication of CCABG at Siyami Ersek Thoracic and Cardiovascular Surgery Center from January 2001 through June 2007. During this period, 10,130 CCABG were performed and 21 patients (0.20%) with PIAD were identified. We compared variables for these 21 patients with 603 patients without PIAD (control group).
Results:
PIAD occurred intraoperatively in 19 patients (90%) and during the early postoperative period (first 6 hours) in 2 patients (10%) who underwent CCABG. Dissections were noticed after removal of the aortic crossclamp in 11 patients, during aortic cannulation in 3 patients, and after removal of the partial-occlusion clamp in 5 patients. Patients with and without PIAD differed significantly in regard to sex (P = .05), history of hypertension (P = .001), and history of severe concomitant peripheral arterial disease (PAD) (P = .001). The diameter of the aorta was significantly wider in patients with PIAD. (3.83 +/- 0.9 vs 2.93 +/- 0.46 cm, P = .019). The occurrence of high cardiopulmonary bypass (CPB) pressure (>==120 mmHg) was significantly higher in the PIAD patients than the non-PIAD patients (28.6% vs 3.3%, P = .0001). Seven PIAD patients (33.3%) died preoperatively and 3 (14.2%) died postoperatively.
Conclusion:
PIAD is frequently fatal. Risk factors for PIAD during or after CCABG include female sex, history of PAD and hypertension, increased aortic diameter, and high CPB pressure.
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