Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cryptococcal Meningitis01:27

Cryptococcal Meningitis

Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Cytomegalovirus Disease01:27

Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A refined porcine lumbar spinal cord injury model facilitating postoperative care.

IBRO neuroscience reports·2026
Same author

Evidence for a Spectral Break or Curvature in the Spectrum of Astrophysical Neutrinos from 5 TeV to 10 PeV.

Physical review letters·2026
Same author

[Smartphone Funduscopic Examination by Medical Students: The FUSOMED Project].

Journal francais d'ophtalmologie·2025
Same author

Search for Extremely-High-Energy Neutrinos and First Constraints on the Ultrahigh-Energy Cosmic-Ray Proton Fraction with IceCube.

Physical review letters·2025
Same author

Short- and long-term outcomes of 14 dogs with single congenital extrahepatic portosystemic shunts attenuated with a percutaneously controlled hydraulic occluder.

New Zealand veterinary journal·2025
Same author

Measurement of Atmospheric Neutrino Oscillation Parameters Using Convolutional Neural Networks with 9.3 Years of Data in IceCube DeepCore.

Physical review letters·2025
Same journal

Peripheral polyneuropathy in three puppies temporally associated with canine parvovirus infection resembling acute polyradiculoneuritis.

Journal of comparative pathology·2026
Same journal

Immunohistochemical characterization of immune cell and metabolic markers in canine prostate carcinoma.

Journal of comparative pathology·2026
Same journal

Pigmented dermal duct tumour (Winkelmann-McLeod type poroma) in a ring-tailed lemur (Lemurcatta).

Journal of comparative pathology·2026
Same journal

Pathological findings in 61 free-ranging leopards (Panthera pardus) from the Greater Kruger National Park, South Africa. Part Two: non-parasitic conditions.

Journal of comparative pathology·2026
Same journal

Pathogenesis of proliferative enteropathy caused by Lawsoniaintracellularis.

Journal of comparative pathology·2026
Same journal

Extraskeletal osteosarcoma in two Guinea pigs (Cavia porcellus).

Journal of comparative pathology·2026
See all related articles

Related Experiment Video

Updated: Jul 1, 2026

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
07:43

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model

Published on: August 5, 2021

Spinal cryptococcoma in an immunocompetent cat.

S Belluco1, J L Thibaud, J Guillot

  • 1Unité d'Anatomie-Pathologique, UMR 703 INRA/ENVN, Ecole Nationale Vétérinaire de Nantes, France.

Journal of Comparative Pathology
|September 12, 2008
PubMed
Summary
This summary is machine-generated.

A rare spinal cord fungal infection, cryptococcoma, occurred in an immunocompetent cat. This case highlights Cryptococcus neoformans var. grubii as a potential pathogen in feline neurological disease.

More Related Videos

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
05:39

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

A Catheter-Related Candida albicans Infection Model in Mouse
03:24

A Catheter-Related Candida albicans Infection Model in Mouse

Published on: March 22, 2024

Related Experiment Videos

Last Updated: Jul 1, 2026

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
07:43

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model

Published on: August 5, 2021

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
05:39

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice

Published on: December 27, 2024

A Catheter-Related Candida albicans Infection Model in Mouse
03:24

A Catheter-Related Candida albicans Infection Model in Mouse

Published on: March 22, 2024

Area of Science:

  • Veterinary Neurology
  • Mycology
  • Immunology

Background:

  • Primary spinal cord fungal infections are rare, especially in immunocompetent animals.
  • Cryptococcosis is caused by Cryptococcus neoformans, a yeast often associated with birds.

Observation:

  • An 11-year-old immunocompetent cat presented with progressive paralysis.
  • Diagnostic workup ruled out common feline infectious diseases.
  • Necropsy revealed a spinal cord lesion with granulomatous inflammation and yeast cells.

Findings:

  • Histopathology confirmed severe granulomatous inflammation and encapsulated yeast cells within the spinal cord lesion.
  • Immunohistochemistry identified the yeast as Cryptococcus neoformans var. grubii.
  • Microscopic findings included necrosis, digestion chambers, Gitter cells, spheroids, and lymphocytic perivascular cuffs.

Implications:

  • This case expands the understanding of Cryptococcus neoformans var. grubii pathogenicity in felines.
  • It underscores the importance of considering fungal infections in feline neurological cases, even in immunocompetent individuals.
  • The pigeon-rich environment suggests a potential source of exposure.