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Updated: Jul 1, 2026

Quantitative Analysis of Cellular Composition in Advanced Atherosclerotic Lesions of Smooth Muscle Cell Lineage-Tracing Mice
Published on: February 20, 2019
[Influence of gender on development and prognosis of atherosclerosis obliterans]
Bin Chen1, Zhi-Hui Dong, Wei-Guo Fu
1Department of Vascular Surgery, Zhongshan Hospital, Fudan University, Shanghai 200032, China. binchen@133sh.com
Objective:
To evaluate the influence of gender on the development and prognosis of atherosclerosis obliterans (ASO).
Methods:
Eight hundred and forty-two patients with ASO were treated from January 2000 to February 2007. The clinical data were retrospectively collected. And the influence of gender on the development and prognosis of ASO was investigated.
Results:
Among the 842 patients, 661 were male and 181 were female. The ratio of male to female was 3.65 : 1.00, and the ratio decreased with increasing age. The mean age of male and female patients were (71.7 +/- 9.0) years and (75.7 +/- 6.8) years, respectively. Significantly more iliac lesions occurred in male patients than in female, while female patients experienced more infrainguinal lesions. The coexistence rate of diabetes and amputation rate were significantly higher in female patients than in male (46.4%/24.7% and 16.0%/9.1%, respectively).
Conclusion:
The female patients with ASO appear to have poorer prognosis than the male, despite their lower incidence of ASO.
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