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Updated: Jul 1, 2026

Use of Ultra-high Field MRI in Small Rodent Models of Polycystic Kidney Disease for In Vivo Phenotyping and Drug Monitoring
Published on: June 23, 2015
[Imaging tests in CKD].
1Department of Nephrology and Kidney and Dialysis Center, Shonan Kamakura General Hospital.
Imaging tests aid in diagnosing chronic kidney disease (CKD) by evaluating kidney function and structure. This review covers ultrasound, CT angiography, and MRI angiography, noting risks like nephrogenic systemic fibrosis.
Area of Science:
- Nephrology
- Radiology
- Medical Imaging
Context:
- Chronic kidney disease (CKD) diagnosis often relies on imaging to assess kidney pathophysiology.
- Conventional and advanced imaging techniques are crucial for evaluating renal anatomy and hemodynamics in CKD patients.
Purpose:
- To review the clinical applications of various imaging modalities in managing chronic kidney disease.
- To highlight the diagnostic utility of ultrasonography, CT angiography, and MRI angiography in CKD.
- To emphasize the risks associated with contrast media, specifically nephrogenic systemic fibrosis.
Summary:
- Gray-scale ultrasonography assesses renal anatomy, while duplex Doppler ultrasound evaluates renal hemodynamics.
- Magnetic resonance angiography and multi-detector row computed tomography angiography offer high sensitivity and specificity for diagnosing renal artery stenosis.
- The review discusses the clinical use of these imaging tests in CKD and the potential risks of gadolinium-based contrast media.
Impact:
- Provides a comprehensive overview of imaging techniques for CKD diagnosis and management.
- Informs clinicians about the benefits and risks of specific imaging modalities, aiding in patient care decisions.
- Highlights the importance of considering contrast-related complications like nephrogenic systemic fibrosis in CKD patients undergoing imaging procedures.
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