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A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection
Published on: February 2, 2022
Renal transplantation in patients with a small bladder
1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Transplantation Proceedings
|September 16, 2008
Summary
Kidney transplantation is successful in patients with small bladders, achieving comparable outcomes to those with normal bladder capacity. Pre-transplant bladder expansion is not necessary for successful renal allografts.
Area of Science:
- Nephrology
- Urology
- Transplantation Surgery
Background:
- Small bladder capacity (<100 mL) presents surgical challenges in kidney transplantation.
- Bladder rehabilitation can be difficult in end-stage renal disease patients with small bladders.
Purpose of the Study:
- To evaluate clinical outcomes of kidney transplantation in patients with small bladders.
- To compare outcomes between patients with small (<100 mL) and normal (≥100 mL) bladder capacities.
Main Methods:
- Retrospective study of 345 kidney transplant recipients (2002-2006).
- Patients classified into Group A (<100 mL bladder capacity) and Group B (≥100 mL).
- Clinical outcomes analyzed: serum creatinine, bladder capacity, complications, urinary tract infections (UTIs), and graft survival.
Main Results:
- Group A patients had longer dialysis duration and more cadaveric transplants.
- No significant difference in surgical complications or UTIs requiring admission between groups.
- Similar serum creatinine levels and 5-year graft survival rates (100% vs 92.4%) between groups.
Conclusions:
- Renal transplantation is successful in patients with small bladders, similar to those with normal bladder size.
- Programmed bladder training or surgical expansion appears unnecessary for successful outcomes.
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