Case of adult mumps infection after renal transplantation

S B Park1, K B Jin, E A Hwang

  • 1Department of Internal Medicine, Kidney Institute, Keimyung University, Dongsan Medical Center, Daegu, Korea. sbpark@dsmc.or.kr

Transplantation Proceedings
|September 16, 2008
PubMed

Insights

Mumps infection is rare in kidney transplant patients. Reducing immunosuppression helped a patient with mumps parotitis recover satisfactorily.

Area of Science:

  • Virology
  • Immunology
  • Nephrology

Background:

  • Opportunistic viral infections are significant complications following organ transplantation.
  • Mumps virus infections are infrequently observed in renal transplant recipients.

Observation:

  • A 23-year-old female renal transplant recipient on immunosuppressive therapy presented with bilateral infra-auricular pain and swelling.
  • Clinical symptoms were accompanied by positive mumps IgM and IgG antibodies, elevated serum amylase, and enlarged parotid glands on CT scan.

Findings:

  • The patient was diagnosed with mumps parotitis.
  • Immunosuppressive therapy, including tacrolimus, prednisolone, and mycophenolate mofetil, was subsequently reduced.

Implications:

  • This case highlights mumps parotitis as a potential opportunistic infection in renal transplant recipients.
  • Management involving the reduction of immunosuppression led to a favorable clinical outcome, suggesting a viable therapeutic strategy.

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