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Updated: Jul 1, 2026

Murine Renal Transplantation Procedure
Published on: July 10, 2009
Case of adult mumps infection after renal transplantation
1Department of Internal Medicine, Kidney Institute, Keimyung University, Dongsan Medical Center, Daegu, Korea. sbpark@dsmc.or.kr
Abstract:
Viruses are the most common cause of opportunistic infections, important complications of transplantation. Mumps infection in renal transplant recipients is uncommon. This report focused on a 23-year-old woman who received immunosuppressive therapy based on tacrolimus, prednisolone, and mycophenolate mofetil for renal transplantation. Sixteen months after transplantation, she was admitted with pain and swelling in both infra-auricular areas. Laboratory findings demonstrated positive mumps IgM and IgG antibodies and an increased serum amylase level. Computed tomography revealed both parotid glands to be diffusely enlarged. After the diagnosis of mumps parotitis, the patient's immunosuppression was reduced and the clinical course was satisfactory.
Insights
Mumps infection is rare in kidney transplant patients. Reducing immunosuppression helped a patient with mumps parotitis recover satisfactorily.
Area of Science:
- Virology
- Immunology
- Nephrology
Background:
- Opportunistic viral infections are significant complications following organ transplantation.
- Mumps virus infections are infrequently observed in renal transplant recipients.
Observation:
- A 23-year-old female renal transplant recipient on immunosuppressive therapy presented with bilateral infra-auricular pain and swelling.
- Clinical symptoms were accompanied by positive mumps IgM and IgG antibodies, elevated serum amylase, and enlarged parotid glands on CT scan.
Findings:
- The patient was diagnosed with mumps parotitis.
- Immunosuppressive therapy, including tacrolimus, prednisolone, and mycophenolate mofetil, was subsequently reduced.
Implications:
- This case highlights mumps parotitis as a potential opportunistic infection in renal transplant recipients.
- Management involving the reduction of immunosuppression led to a favorable clinical outcome, suggesting a viable therapeutic strategy.
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