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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Potential uses of computed tomography for management of heart failure patients with dyssynchrony
Quynh A Truong1, Udo Hoffmann, Jagmeet P Singh
1Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA.
Insights
Cardiac resynchronization therapy (CRT) can be improved by using cardiac computed tomography. This single imaging modality can assess anatomic, mechanical, and structural issues for better patient selection and lead placement in heart failure management.
Area of Science:
- Cardiology
- Medical Imaging
- Biomedical Engineering
Background:
- Cardiac resynchronization therapy (CRT) is crucial for managing heart failure.
- Patient selection and left ventricular lead placement are key to CRT success.
- Current imaging lacks a single modality for comprehensive assessment of anatomic, mechanical, and structural factors.
Purpose of the Study:
- To explore cardiac computed tomography (CT) as a unified imaging solution for CRT.
- To assess CT's capability in providing functional and anatomic information.
- To investigate integrating CT with real-time fluoroscopy for improved procedural guidance.
Main Methods:
- Conceptual presentation of cardiac CT for comprehensive cardiomyopathy assessment.
- Discussion of CT's potential for evaluating venous anatomy, mechanical dyssynchrony, and scar location.
- Exploration of integrating CT data with real-time fluoroscopy.
Main Results:
- Cardiac CT offers a potential single-modality approach to gather diverse patient data.
- CT can provide both anatomic and functional information relevant to CRT.
- Integration with fluoroscopy may enhance procedural accuracy and efficiency.
Conclusions:
- Cardiac CT presents a promising concept for a unified imaging approach in CRT.
- This modality could address limitations of current techniques in patient selection and lead placement.
- Further development may lead to improved outcomes for heart failure patients undergoing CRT.
Abstract:
Cardiac resynchronization therapy has become an integral part in the step-care approach to manage patients with heart failure. Cardiac imaging remains central to appropriate patient selection and optimal left ventricular lead placement, both of which are important determinants of response to cardiac resynchronization therapy. One of the biggest limitations with current imaging modalities is the inability of a single technique to address each, the anatomic (venous anatomy), mechanical (dyssynchrony), and structural (extent of scar location) issues accompanying cardiomyopathy. We present here the potential concept of using cardiac computed tomography as a single modality to acquire functional and anatomic information, and also to show the possibility of integrating this with real time fluoroscopy.
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