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Updated: Jul 1, 2026

Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
Published on: July 25, 2020
[Impact of tumorcytogenetics in tumor diagnostics]
Friedel Wenzel1, Benno Röthlisberger
1Abteilung Medizinische Genetik, Universitäts-Kinderspital beider Basel, Basel.
Abstract:
Most tumors are caused by acquired somatic mutations. For half a century now chromosomal anomalies in hematological neoplasia and to a much less extent in solid tumors are investigated by conventional cytogenetics. During all this time the significance of genetic factors for tumor classification increased continuously. Especially for haematological neoplasia, besides <
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