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Related Concept Videos

pV-Diagrams01:18

pV-Diagrams

The pV diagram, which is a graph of pressure versus volume of the gas under study, is helpful in describing certain aspects of the substance. When the substance behaves like an ideal gas, the ideal gas equation describes the relationship between its pressure and volume. On a pV diagram, it is common to plot an isotherm, which is a curve showing p as a function of V with the number of molecules and the temperature fixed. Then, for an ideal gas, the product of the pressure of the gas and its...
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Bode Plots

Bode plots are graphical tools that use logarithmic scales for frequency on the x-axis and gain in decibels on the y-axis. This logarithmic method allows a wide range of frequencies to be compactly displayed, enabling the analysis of component effects on circuit behavior across a broad frequency spectrum.
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Fluid Pressure over Flat Plate of Variable Width01:02

Fluid Pressure over Flat Plate of Variable Width

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Generation of Warfighter Avatars from Weapon Training Scene Images for Blast Exposure Simulations
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BOV--a web-based BLAST output visualization tool.

Rajesh Gollapudi1, Kashi Vishwanath Revanna, Chris Hemmerich

  • 1Center for Genomics and Bioinformatics, Indiana University, Bloomington, Indiana, USA. rajgolla@indiana.edu

BMC Genomics
|September 17, 2008
PubMed
Summary
This summary is machine-generated.

The BLAST Output Visualization Tool (BOV) offers a user-friendly web interface for visualizing complex sequence similarity search results. This tool aids biologists in interpreting genomic data by interactively displaying matching regions in BLAST alignments.

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Area of Science:

  • Genomics
  • Bioinformatics
  • Computational Biology

Background:

  • BLAST is a widely used tool for genomic research, often employed by biologists without extensive bioinformatics training.
  • Increasing sequence data necessitates efficient management and interpretation of complex BLAST batch query results.
  • Existing software lacks robust visualization tools for complex BLAST pair-wise alignments.

Purpose of the Study:

  • To develop a web-based program, the BLAST Output Visualization Tool (BOV), for interactive visualization of BLAST alignment results.
  • To provide a user-friendly interface for dissecting complex matching patterns between query and database sequences.

Main Methods:

  • Users upload standard BLAST output (pair-wise alignment format) to the web server.
  • The program extracts alignment coordinates to plot matching regions as colored lines or trapezoids.
  • Interactive control panels allow detailed exploration of plotted regions and raw sequence alignments.

Main Results:

  • BOV successfully visualizes matching regions in BLAST pair-wise alignments.
  • Users can interactively explore highlighted regions and examine raw sequence data.
  • Tutorials are available to guide users through the software's features.

Conclusions:

  • BOV offers a user-friendly web interface for visualizing BLAST output for diverse genomic problems.
  • The tool is particularly valuable for identifying co-linearity, duplication, translocation, and inversion among sequences.
  • BOV is accessible via a web server and available for free local installation.