Cold panniculitis
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Published on: January 21, 2020
Alicia Quesada-Cortés1, Lucía Campos-Muñoz, Rosa M Díaz-Díaz
1Department of Dermatology, Hospital Universitario La Paz, Universidad Autónoma, Paseo La Castellana, No. 261, 28046 Madrid, Spain. aliciaqc@hotmail.com
Abstract:
Cold panniculitis has been described in children and young women following cold exposure. Histopathologically, cold panniculitis shows a mostly lobular panniculitis, which consists of an infiltrate of lymphocytes and histiocytes in the fat lobules. Usually, the dermis shows a superficial and deep perivascular infiltrate mostly composed of lymphocytes, with no vasculitis. Inflammation is most intense at the dermal-subcutaneous junction. Differential diagnosis of cold panniculitis should be established with subcutaneous fat necrosis of the newborn, sclerema neonatorum, poststeroid panniculitis, chilblains, and frostbites.
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