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Published on: August 16, 2021
Analytic reviews: cardiogenic shock with preserved systolic function: a reminder
Kanu Chatterjee1, Dana McGlothlin, Andrew Michaels
1Division of Cardiology, Department of Medicine, University of California-San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA. chatterj@medicine.ucsf.edu
Insights
Cardiogenic shock can occur with preserved ejection fraction, differing from typical cases. Prompt diagnosis and treatment of this specific condition lead to a favorable prognosis.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Cardiogenic shock typically involves reduced left ventricular systolic function.
- However, cardiogenic shock can also manifest in patients with preserved ejection fraction.
Purpose of the Study:
- To review the distinct etiologies and pathophysiology of cardiogenic shock with preserved ejection fraction.
- To discuss the diagnostic and therapeutic approaches for this specific patient group.
Main Methods:
- Literature review of studies on cardiogenic shock with preserved ejection fraction.
- Analysis of etiological factors, pathophysiological mechanisms, diagnostic criteria, and treatment strategies.
Main Results:
- Cardiogenic shock with preserved ejection fraction has unique causes and mechanisms compared to reduced ejection fraction.
- Therapeutic strategies differ significantly between these two presentations.
Conclusions:
- Prompt diagnosis and appropriate treatment are crucial for a favorable prognosis in acute cardiogenic shock with preserved ejection fraction.
- Understanding the specific characteristics of this syndrome is essential for effective patient management.
Abstract:
Although cardiogenic shock, whether acute or chronic, most frequently results from depressed left ventricular systolic function, the same syndrome can occur in patients with preserved systolic function. The etiologies and the pathophysiology of the syndrome of cardiogenic shock with preserved ejection fraction are distinctly different from those with reduced ejection fraction. The therapeutic approaches are also different. The prognosis of the patients with acute subset of this syndrome is very favorable, provided prompt diagnosis is made and appropriate treatment is provided. In this review, the important causes, pathophysiology, diagnosis, and therapies of patients with "cardiogenic shock with preserved ejection fraction'' are discussed.
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