Corneal thickness and anterior chamber depth by Orbscan in normal and primary open-angle glaucoma patients in Korea

To characterize central corneal thickness (CCT), thinnest corneal thickness, and anterior chamber depth (ACD) in Koreans and assess their variation between nonglaucomatous eye and eye with primary open-angle glaucoma (POAG).

This observational cross-sectional study included patients previously diagnosed as POAG (n=226), and nonglaucomatous patients (n=580). Thinnest corneal thickness, CCT, and ACD were measured by Orbscan. Means of measurements and their correlations with glaucoma diagnosis, age, spherical equivalent, and sex were evaluated.

No difference was seen in CCT among POAG and nonglaucomatous subjects (532.7 and 537.0 microm, respectively, P=0.224). Neither thinnest corneal thickness was different between these groups (P=0.150). There was no statistically significant difference in mean central or thinnest corneal thickness between eyes with different sex. Central or thinnest corneal thicknesses were not correlated with age. ACD was inversely correlated with age and refractive error (both, P<0.0001).

In Koreans, neither central nor thinnest corneal thickness was different between POAG and nonglaucomatous eyes. There was an inverse relationship between age and ACD.