Multi-spectral angular domain optical imaging in biological tissues using diode laser sources
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Updated: Jul 1, 2026

Bioorthogonal Chemical Imaging of Cell Metabolism Regulated by Aromatic Amino Acids
Published on: May 12, 2023
Fartash Vasefi1, Bozena Kaminska, Paulman K Y Chan
1Simon Fraser University, School of Engineering Science, 8888 University Drive, Burnaby, BC, Canada. fartash@ieee.org
Abstract:
Angular Domain Imaging (ADI) employs micromachined angular filter to detect non-scattered photons that pass through the micro-scale tunnels unattenuated while scattered photons are rejected. This paper describes the construction of an ADI system utilizing diode lasers at three different wavelengths in the range of the red and near infrared spectrum. Experiments are performed to verify the feasibility of ADI at multi-wavelengths. ADI results of chicken breast as a biological scattering medium are presented for different thicknesses. A spatial resolution of <0.5 mm is achieved with 5 mm thick chicken breast using a 975 nm diode laser source.
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