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Updated: Jun 30, 2026

Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
Acute mesenteric ischemia
Jiri Vokurka1, Juraj Olejnik, Vaclav Jedlicka
1lst Department of Surgery, Masaryk University, St. Anne's Hospital, Pekarska 53, 656 91 Brno, Czech Republic. vokurka@med.muni.cz
Background/Aims:
Acute mesenteric ischemia (AMI) is a serious disease in old age with low incidence but with a very high mortality rate (60-70%). The etiology is either primary (embolism or thrombosis of mesenteric arteries or veins, non-occlusive mesenteric ischemia) or secondary (mechanical obstruction such as intestinal volvulus, intussusception, tumor-caused compression). Independent of the origin of the illness, the clinical-pathological picture is the same: intestinal ischemia with subsequent necrosis. The aim of this study was to ascertain which underlying conditions lead to increased probability of development of acute mesenteric ischemia.
Methods:
Two hundred and fifteen patients with a primary form of AMI were treated in the years 1991-2007, in the 1st Clinic of Surgery in Brno, Czech Republic and in the Department of General Surgery, Derer's University Hospital in Bratislava, Slovak Republic; the results of the treatment have been statistically evaluated.
Conclusion:
The probability of arterial mesenteric ischemia development rises significantly (p < 0.05) in patients with a history of atrial fibrillation and/or myocardial infarction. This probability is also significantly higher in smokers with symptoms of hypertension and clinical signs of abdominal angina (p < 0.05).
Insights
Acute mesenteric ischemia (AMI) risk increases with atrial fibrillation, myocardial infarction, smoking, hypertension, and abdominal angina. Identifying these risk factors is crucial for early intervention in this severe condition.
Area of Science:
- Gastroenterology
- Vascular Surgery
- Geriatric Medicine
Background:
- Acute mesenteric ischemia (AMI) is a critical condition in the elderly, characterized by high mortality rates (60-70%).
- Etiologies include primary vascular events (embolism, thrombosis) or secondary mechanical obstructions.
- Regardless of origin, AMI leads to intestinal ischemia and necrosis.
Purpose of the Study:
- To identify underlying conditions that increase the likelihood of developing acute mesenteric ischemia.
Main Methods:
- A retrospective statistical analysis of 215 patients with primary AMI.
- Data collected from the 1st Clinic of Surgery in Brno, Czech Republic, and Derer's University Hospital in Bratislava, Slovak Republic.
- Treatment outcomes evaluated between 1991 and 2007.
Main Results:
- A history of atrial fibrillation and/or myocardial infarction significantly increases the probability of arterial mesenteric ischemia (p < 0.05).
- Smokers presenting with hypertension and abdominal angina also show a significantly higher probability of developing AMI (p < 0.05).
Conclusions:
- Atrial fibrillation, myocardial infarction, smoking, hypertension, and abdominal angina are significant risk factors for acute mesenteric ischemia.
- Early identification of these risk factors can aid in the timely diagnosis and management of AMI.
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