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Related Experiment Video

Updated: Jun 30, 2026

High-throughput Measurement of Gut Transit Time Using Larval Zebrafish

High-throughput Measurement of Gut Transit Time Using Larval Zebrafish

Published on: October 23, 2018

Modeling bioaccumulation using characteristic times.

Adrian Powell¹, Don Mackay, Eva Webster

¹Centre for Environmental Modeling and Chemistry, Trent University, 1600 West Bank Drive, Peterborough, Ontario K9J 7B8, Canada.

Environmental Toxicology and Chemistry

|September 19, 2008

Summary

This summary is machine-generated.

A novel bioaccumulation model using characteristic times offers new insights into chemical uptake and loss processes in aquatic and terrestrial organisms. This approach complements existing methods for assessing bioaccumulation and biomagnification.

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Published on: August 29, 2014

Area of Science:

Environmental Science
Ecotoxicology
Biogeochemistry

Background:

Bioaccumulation models are crucial for understanding chemical contaminant dynamics in organisms.
Existing models like concentration-rate constant and fugacity have limitations in clearly defining uptake and loss rates.

Purpose of the Study:

To derive and apply a new mass balance model for bioaccumulation using characteristic time parameters.
To demonstrate the mathematical equivalence of the new formulation with existing models.
To provide additional insights into bioaccumulation processes.

Main Methods:

Developed a new mass balance model based on characteristic time parameters.
Mathematically demonstrated equivalence to concentration-rate constant and fugacity models.
Applied the model to water-respiring (trout) and air-respiring (wolf) organisms.

Main Results:

The characteristic time formulation is mathematically equivalent to traditional bioaccumulation models.
Characteristic times offer readily identifiable chemical and biological significance for uptake and loss rates.
The model provides insights into the relative importance of different bioaccumulation processes.

Conclusions:

The characteristic time formulation offers valuable complementary insights to conventional bioaccumulation modeling.
This approach enhances understanding of chemical dynamics in diverse organisms.
The model aids in evaluating bioenergetic consistency and the significance of various uptake/loss pathways.