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Related Experiment Videos

Intractable hiccup induced by brainstem lesion.

S M al Deeb1, H Sharif, K al Moutaery

  • 1Dept. of Clinical Neuroscience, Riyadh Armed Forces Hospital, Kingdom of Saudi Arabia.

Journal of the Neurological Sciences
|June 1, 1991
PubMed
Summary
This summary is machine-generated.

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Intractable hiccups can stem from brainstem lesions, not just psychogenic causes. Magnetic resonance imaging (MRI) is crucial for diagnosing these lesions, unlike computed tomography.

Area of Science:

  • Neurology
  • Neuroimaging
  • Infectious Diseases

Background:

  • Intractable hiccup is a debilitating condition often misdiagnosed.
  • Brainstem lesions are an underrecognized cause of persistent hiccups.

Observation:

  • Four patients with brainstem lesions presented with intractable hiccup and neurological signs.
  • Magnetic resonance imaging (MRI) identified brainstem infarction and central nervous system tuberculomas.
  • High-resolution enhanced computed tomography failed to detect some brainstem lesions.

Findings:

  • Central nervous system tuberculomas responded well to antituberculous chemotherapy, resolving hiccups.
  • Brainstem infarction was identified as a cause of intractable hiccup.
  • Hiccup may represent myoclonus of the 'inspiratory solitary nucleus' due to loss of inhibitory control.

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Implications:

  • MRI is vital for diagnosing brainstem lesions causing intractable hiccup.
  • Early diagnosis and treatment of central nervous system tuberculomas can resolve hiccups.
  • Understanding the neuroanatomical network of hiccup formation aids in management.