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Primary intratesticular spindle cell tumors: interdigitating dendritic cell tumor and inflammatory myofibroblastic
Manuel Nistal1, Pilar Gonzalez-Peramato, Alvaro Serrano
1Department of Pathology, Hospital La Paz, Madrid, Spain.
Abstract:
Spindle cell neoplasms arising in the testis are uncommon; most cases belong to the category of gonadal stromal tumors, and the presence of distinctive clinical and pathological features usually lead to a definitive diagnosis. In some instances, however, the diagnosis of these tumors can be challenging and special techniques are needed. The present study reports 2 unusual cases of primary intratesticular tumors showing a striking morphology, characterized by spindle to stellate cells in a lymphoid background. The diagnosis of interdigitating dendritic cell tumor and inflammatory myofibroblastic tumor was established in the 2 cases, and their probable origin in cells of the accessory immune system is discussed. Although both tumors share similar histological features, their immunohistochemical profiles were decisive for a definitive diagnosis.
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