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Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome
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Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

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Comparison of aortic pulse wave velocity measured by three techniques: Complior, SphygmoCor and Arteriograph

Marek W Rajzer1, Wiktoria Wojciechowska, Marek Klocek

  • 11st Department of Cardiology and Hypertension, Institute of Cardiology, Jagiellonian University Medical College, Krakow, Poland. rajzer37@interia.pl

Journal of Hypertension
|September 23, 2008
PubMed

Insights

Arterial stiffness measurement devices show significant differences in aortic pulse wave velocity (PWV) due to varied distance calculations. Standardizing traveled distance measurement is recommended for consistent arterial stiffness assessment.

Area of Science:

  • Cardiovascular Physiology
  • Hypertension Research
  • Medical Device Technology

Background:

  • European hypertension guidelines recommend arterial stiffness measurement.
  • Carotid-femoral pulse wave velocity (PWV) > 12 m/s indicates subclinical organ damage.
  • Variations in PWV measurement techniques warrant investigation.

Purpose of the Study:

  • Compare aortic PWV measurements using Complior, SphygmoCor, and Arteriograph devices.
  • Assess the impact of transit time and traveled distance on PWV values.
  • Evaluate device-specific methodologies in hypertension assessment.

Main Methods:

  • Aortic PWV measured in 64 hypertensive patients.
  • Randomized, single-visit assessment using Complior, SphygmoCor, and Arteriograph.
  • Analysis of pulse wave transit time and traveled distance variations.

Main Results:

  • Complior yielded significantly higher PWV (10.1 m/s) than SphygmoCor (8.1 m/s) and Arteriograph (8.6 m/s).
  • No significant PWV difference between SphygmoCor and Arteriograph.
  • Significant differences in traveled distance measurements between devices, not transit times.

Conclusions:

  • Discrepancies in PWV measurements stem mainly from varied traveled distance calculations.
  • Standardized principles for measuring traveled distance are necessary.
  • Direct carotid-femoral distance is recommended due to its use in prognosis studies.
Abstract

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